This is the statistical evaluation of protein specific glycosylation. Glycosylation is a very significant post-translational modification of proteins that binds glycans onto the protein to modulate the structure, function and interface with other systems. This can be anything from N- to O-linked glycosylation, and may have implications for protein stability, activity and cell signaling. Tracking glycosylation can tell scientists what protein is and how it is used for health and illness.

Understanding glycosylation is vital for several reasons:

• Biochemical Activity: Glycans are essential for folding, stability, and biomolecular interaction. These functions can also be impacted by modifications to glycosylation.
• Pathology: The glycosylation state may vary with disease such as cancer, autoimmune disorders, etc. These changes can be used to find biomarkers and detect disease.
• Biopharmaceutical Research: To ensure safety and efficacy, therapeutic proteins require regular glycosylation. Regulators demand a full glycan profile to ensure biopharmaceuticals are quality-controlled.